The most successful techniques in early detection of fetal abnormalities

5D CNS

Fetal brain biometry is an essential part of the sonographic examination to estimate the gestational age of the fetus and to detect congenital abnormalities. However, due to complex anatomy of fetal brain, fetal movement and operator dependency, it is difficult to measure the biometrics and identify all relevant cerebral structures.

Fetal central nervous system (CNS) anomalies have been diagnosed by the combination of recognizable markers including the lateral ventricles, the cerebellum and the cavum septic pellucid (CSP).

A novel semi-automated technology, 5D CNS, significantly improves accuracy and reproducibility as well as reduces intra-/inter-observer variability by combining fetal brain measurements and the automated

process.

5D CNS displays three standardized planes such as trans thalamic view, trans ventricular view and trans cerebellar view including mid-sagittal view of the fetal brain. And it automatically labels the measurements of biparietal diameter (BPD), head circumference (HC) and occipito-frontal diameter (OFD) as well as transverse cerebellar diameter (CEREB) for qualitative evaluation of the fetal growth and some cerebral anomalies. Also, the thickness of the atrium (atrial width) of the lateral ventricles (Vp) is measured for assessing the integrity of the ventricular system and the size of the cisterna magna (CM) is provided by 5D CNS.

5D CNS+

Central nervous system (CNS) malformations are the most common defects of all congenital abnormalities. Basic examination of the fetal brain includes the evaluation of low-risk pregnancies with three axial planes commonly referred to as the trans ventricular plane, the trans cerebellar plane and trans thalamic plane. The detailed evaluation (fetal neurosensorial) of the fetal CNS is useful in the evaluation of an increased risk of CNS anomalies including cases in which the basic examination identifies suspicious findings. However, this examination requires a grade of expertise and sophisticated ultrasound system.

A semi-automated technology, 5D CNS+ of WS80A with Elite, provides nine planes (axial, coronal, sagittal planes) of fetal brain and biometric measurements. Especially, in addition of sagittal and coronal planes in the screening evaluation of fetal CNS anatomy, 5D CNS+ helps to improve the diagnostic efficacy and provide capability of diagnosing anomalies of the midline and posterior fossa which cannot be seen by the axial planes. 5D CNS+ will give further benefits on prenatal diagnosis, management and prognosis of fetal central nervous system.

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